International Journal of Terahertz Science and Technology
  TST >> Vol.12, No.1, March 2019: PP. 1-11

(Invited Paper)Terahertz in-vivo studies: improving experimental techniques to eliminate variables

Rayko Ivanov Stantchev 1, Qiushuo Sun 1, Shuting Fan 2, Xuequan Chen 1, and Emma Pickwell-MacPherson 1, 3*
1 Department of Electronic Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong
2 College of Electronic Science and Technology, Shenzhen University, 3688 Nanhai Rd, Shenzhen, Guangdong, China 518060
3 Department of Physics, Warwick University, Coventry, UK
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Abstract: THz spectroscopic imaging is highly sensitive to water content, and as abnormal water content is usually indicative of afflictions THz imaging has great medical potential in early-stage disease diagnosis. However, clinical use requires fast acquisition, repeatability and cost-effective, reliable equipment, which is not yet offered by THz technology. In this work we have reviewed the methods and technologies that have the potential of allowing the transference of THz from the laboratory to the hospital. First, we discuss the need for reliable sample characterization and the calibration methods that overcome the relevant problems. Second, we discuss the usefulness of THz in disease diagnosis and further outline how occlusion of the skin must be accounted for accurate diagnosis. Thirdly, we discuss how adaptive sampling and smart image under-sampling can be used to reduce measurement times.

Keywords: Terahertz spectroscopy, Dermatology, Terahertz imaging, Adaptive imaging, THz modulation, Compressed sensing, Scar healing

Received: 2018-8-31

Published: 2019-3-31

Acknowledgments: This work was partially supported by the Research Grants Council of Hong Kong (project numbers 14206717 and 14201415), the Hong Kong Innovation and Technology Fund (project number ITS/371/16), the Royal Society Wolfson Merit Award (EM) and the Hong Kong PhD Fellowship Award (QS).

Cite this article:
Rayko Ivanov Stantchev, Qiushuo Sun, Shuting Fan, Xuequan Chen and Emma Pickwell-MacPherson (Invited Paper) Terahertz in-vivo studies: improving experimental techniques to eliminate variables [J]. International Journal of Terahertz Science and Technology, 2019, Vol.12, No.1: 1-11.  DOI:10.11906/TST.001-011.2019.03.01




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